Boehringer Ingelheim and Mirati Therapeutics, Inc. entered a clinical collaboration to evaluate the combination of BI 1701963, a SOS1::pan-KRAS inhibitor, and MRTX849, a KRAS G12C selective inhibitor in patients with solid tumors that harbor the KRAS G12C mutation. The collaboration will study the potential of this combination in providing more effective and durable responses for patients with lung and colorectal cancers who currently have limited treatment options. Preclinical data suggest ...